Resources

Global challenge of antibiotic-resistant Treponema pallidum

Abstract Syphilis is a multistage infectious disease that is usually transmitted through contact with active lesions of a sexual partner or from an infected pregnant woman to her fetus. Despite...Read More

L .V. Stamm

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December 14, 2021

Interest, concerns, and attitutdes among men who have sex with men and healthcare providers toward prophylactic use of doxycycline against Chlamydia trachomatis infections and syphilis

Abstract Introduction: Prophylactic administration of doxycycline is regarded as a potential new public health strategy to combat the rising rates of Chlamydial trachomatis infections and syphilis among men who have...Read More

Park et al.

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February 09, 2021

High Interest in Syphilis Pre-exposure and Post-exposure Prophylaxis Among Gay, Bisexual and Other Men Who Have Sex With Men in Vancouver and Toronto

Abstract Background: We assessed the acceptability of doxycycline-based syphilis pre-exposure and post-exposure prophylaxis (PrEP/PEP) as well as human immunodeficiency virus (HIV) PrEP/PEP in gay, bisexual, and other men who have...Read More

Fusca et al.

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April 01, 2020

Perceptions of sexually transmissible infection pre-exposure prophylaxis: a qualitative study of high-risk gay and bisexual men in Sydney, New South Wales

Abstract Background: Novel sexually transmissible infection (STI) prevention strategies are needed to combat increasing bacterial STI incidences alongside decreasing condom use among gay and bisexual men (GBM) in Australia. Sexually...Read More

Horn et al.

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March 26, 2020

Use of doxycycline and other antibiotics to prevent STIs among men who have sex with men visiting sexual health clinics in the Netherlands

Abstract A clinical trial (ANRS IPERGAY) among 232 men who have sex with men (MSM) using HIV pre-exposure prophylaxis (HIV-PrEP) showed efficacy of postexposure prophylaxis with doxycycline in reducing chlamydia...Read More

Evers et al.

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December 26, 2019

Knowledge and attitudes of syphilis and syphilis pre-exposure prophylaxis (PrEP) among men who have sex with men in Vancouver, Canada: a qualitative study

Abstract Objectives In British Columbia, Canada, syphilis is at record-high rates, with over 80% of cases in 2017 seen in gay, bisexual and other men who have sex with men...Read More

Nath et al.

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November 04, 2019

Doxycycline Prophylaxis for Bacterial Sexually Transmitted Infections

Abstract Bacterial sexually transmitted infections (STIs) have been increasing over the past 2 decades in gay, bisexual, and other men who have sex with men. With the widespread use of...Read More

Grant et al.

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September 01, 2019

Use of Doxycycline Prophylaxis Against STI Among Gay and Biseaxual Men Taking Pre-Exposure Prophylaxis in Melbourne

Abstract Background Two trials have shown the use of doxycycline prophylaxis could prevent sexually transmitted infections such as chlamydia and syphilis among men who have sex with men (MSM) but...Read More

Chow and Fairley

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July 16, 2019

High Interest in Doxycycline for Sexually Transmitted Infection Postexposure prophylaxis in a Multicity Survey of Men Who Have Sex With Men Using a Social Networking Application

Abstract Current strategies to prevent sexually transmitted infections (STIs) are not controlling the epidemic. The efficacy of doxycycline STI postexposure prophylaxis shows promise in pilot studies, but wider acceptability is...Read More

Spinelli et al.

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October 29, 2018

Post-exposure prophylaxis with doxycycline to prevent sexually transmitted infections in men who have sex with men: an open-label randomised substudy of the ANRS IPERGAY trial

Abstract Background: Increased rates of sexually transmitted infections (STIs) have been reported among men who have sex with men. We aimed to assess whether post-exposure prophylaxis (PEP) with doxycycline could...Read More

Molina et al.

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December 08, 2017

Antimicrobial resistance in Neisseria gonorrhoeae: history, molecular mechanisms and epidemiological aspects of an emerging global threat

Abstract Neisseria gonorrhoeae is the agent of gonorrhea, a sexually transmitted infection with an estimate from The World Health Organization of 78 million new cases in people aged 15-49 worldwide...Read More

Costa-Lourenço APRD, Barros dos Santos KT, Moreira BM, Fracalanzza SEL, Bonelli RR

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October 01, 2017

Doxycycline Prophylaxis to Reduce Incident Syphilis among HIV-Infected Men who have Sex with Men who Continue to Engage in High Risk Sex: A Randomized, Controlled Pilot Study

Abstract Background: Incident syphilis infections continue to be especially prevalent among a core group of HIV-infected men who have sex with men (MSM). Because of synergy between syphilis and HIV...Read More

Bolan et al.

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October 16, 2014

Antibiotic resistance of microbial strains isolated from Korean acne patients

Abstract Over several decades, topical and systemic antibiotics have been the mainstay of treatment for acne vulgaris. The widespread and long-term use of antibiotics in the treatment of acne has...Read More

Moon, S. H. et al.

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July 11, 2012

Chemoprophylaxis Is Likely to Be Acceptable and Could Mitigate Syphilis Epidemics Among Populations of Gay Men

Abstract Background: Over the last decade, syphilis epidemics have resurged around the world, particularly among gay men. An innovative public health response could be the use of chemoprophylaxis. We sought...Read More

Wilson et al.

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July 01, 2011

European surveillance of antimicrobial resistance in Neisseria gonorrhoeae

Abstract Objective: To perform a European sentinel surveillance study for antimicrobial resistance (AMR) in Neisseria gonorrhoeae as part of the European Surveillance of Sexually Transmitted Infections Programme. Methods: From 2006...Read More

Cole, M. J. et al.

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November 01, 2010

Long-term treatment with sub-antimicrobial dose doxycycline has no antibacterial effect on intestinal flora

Abstract Aim: The purpose of this study was to determine if a 9-month regimen of sub-antimicrobial doxycycline (20 mg, bid) had an effect on either the intestinal or the vaginal...Read More

Walker, C. et al.

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October 06, 2005