What is the DISCO study all about?

DISCO stands for Doxycycline as an Intervention for bacterial STI ChemOprophylaxis. It’s a Canadian study, aiming to enroll 560 gay, bisexual and other men who have sex with men (gbMSM), including both cisgender and transgender gbMSM, and transgender women. Participants will be enrolled randomly into one of the two study arms: (1) the doxycycline pre-exposure prophylaxis (PrEP) arm, where they will take one doxycycline pill daily; (2) the doxycycline post-exposure prophylaxis (PEP) arm, where they will take two doxycycline pills within 72 hours of a sexual encounter, to a maximum of six pills per week.